Reproductive immunology explores how a person’s immune system might negatively affect fertility and pregnancy. In some cases, the immune system may mistakenly attack sperm, embryos, or even a developing pregnancy — viewing them as foreign invaders. This immune response can lead to difficulties in conceiving, failed IVF cycles, or recurrent miscarriages.
Our Immunology Protocol helps detect these hidden immune factors and provides targeted treatments to balance the immune system and improve the chances of a successful pregnancy.
Reproductive immunology explores how a person’s immune system might negatively affect fertility and pregnancy. In some cases, the immune system may mistakenly attack sperm, embryos, or even a developing pregnancy — viewing them as foreign invaders. This immune response can lead to difficulties in conceiving, failed IVF cycles, or recurrent miscarriages.
Who Should Consider the Immunology Protocol?
Our fertility specialists may recommend immunology testing for individuals and couples who have experienced:
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Recurrent miscarriage (2 or more consecutive losses)
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Multiple failed IVF or IUI cycles despite good embryo quality
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Unexplained infertility with no clear diagnosis after standard testing
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Autoimmune conditions such as lupus, Hashimoto’s thyroiditis, or rheumatoid arthritis
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Family history of autoimmune disorders
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Elevated natural killer (NK) cells or other immune abnormalities detected previously
Our comprehensive Immunology Protocol at Barbados Fertility Centre involves advanced diagnostic tests to evaluate immune function, including:
Natural Killer (NK) Cell Testing — Assesses levels and activity of NK cells, which can impair implantation if overactive
Antiphospholipid Antibody Screening — Checks for antibodies linked to increased miscarriage risk
Thyroid Antibody Testing — Identifies autoimmune thyroid disorders that affect fertility
Lupus Anticoagulant & Other Blood Clotting Tests — Evaluates risk of clotting disorders that can impact pregnancy
Cytokine & Inflammatory Marker Testing — Measures immune system signalling molecules linked to inflammation
Many patients who previously experienced repeated IVF failures or unexplained miscarriages have successfully conceived and carried healthy pregnancies after following our Immunology Protocol. By addressing underlying immune factors, we optimise implantation and support healthy embryo development — improving your chances of success.